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Somatic mutation detection and classification through probabilistic integration of clonal population information

Somatic mutations are a primary contributor to malignancy in human cells. Accurate detection of mutations is needed to define the clonal composition of tumours whereby clones may have distinct phenotypic properties. Although analysis of mutations over multiple tumour samples from the same patient ha...

詳細記述

保存先:
書誌詳細
出版年:Commun Biol
主要な著者: Dorri, Fatemeh, Jewell, Sean, Bouchard-Côté, Alexandre, Shah, Sohrab P.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355807/
https://ncbi.nlm.nih.gov/pubmed/30729182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0291-z
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