Circulating Pentraxin3-Specific B Cells Are Decreased in Lupus Nephritis

Background: Pentraxin3 (PTX3) is overexpressed in kidneys of patients developing lupus nephritis (LN). Active LN is associated with reduced anti-PTX3 antibodies. However, abnormalities of B cell differentiation against PTX3 have not been characterized in systemic lupus erythematosus (SLE). Objective...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gatto, Mariele, Wiedemann, Annika, Nomovi, Nadja, Reiter, Karin, Schrezenmeier, Eva, Rose, Thomas, Szelinski, Franziska, Lino, Andreia C., Valentino, Sonia, Ghirardello, Anna, Dörner, Thomas, Doria, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355680/
https://ncbi.nlm.nih.gov/pubmed/30740098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00029
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