GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation

BACKGROUND: Glycogen synthase kinase-3β (GSK3β) is a key regulator of cellular homeostasis. In neurons, GSK3β contributes to the control of neuronal transmission and plasticity, but its role in epilepsy remains to be defined. METHODS: Biochemical and electrophysiological methods were used to assess...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Urbanska, Malgorzata, Kazmierska-Grebowska, Paulina, Kowalczyk, Tomasz, Caban, Bartosz, Nader, Karolina, Pijet, Barbara, Kalita, Katarzyna, Gozdz, Agata, Devijver, Herman, Lechat, Benoit, Jaworski, Tomasz, Grajkowska, Wieslawa, Sadowski, Krzysztof, Jozwiak, Sergiusz, Kotulska, Katarzyna, Konopacki, Jan, Van Leuven, Fred, van Vliet, Erwin A., Aronica, Eleonora, Jaworski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355642/
https://ncbi.nlm.nih.gov/pubmed/30502054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.040
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