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Preexposure to Isavuconazole Increases the Virulence of Mucorales but Not Aspergillus fumigatus in a Drosophila melanogaster Infection Model

Breakthrough mucormycosis in patients receiving isavuconazole prophylaxis or therapy has been reported. We compared the impact of isavuconazole and voriconazole exposure on the virulence of clinical isolates of Aspergillus fumigatus and different Mucorales species in a Drosophila melanogaster infect...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Wurster, Sebastian, Lewis, Russell E., Albert, Nathaniel D., Kontoyiannis, Dimitrios P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355575/
https://ncbi.nlm.nih.gov/pubmed/30455245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01896-18
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