Preexposure to Isavuconazole Increases the Virulence of Mucorales but Not Aspergillus fumigatus in a Drosophila melanogaster Infection Model

Breakthrough mucormycosis in patients receiving isavuconazole prophylaxis or therapy has been reported. We compared the impact of isavuconazole and voriconazole exposure on the virulence of clinical isolates of Aspergillus fumigatus and different Mucorales species in a Drosophila melanogaster infect...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Wurster, Sebastian, Lewis, Russell E., Albert, Nathaniel D., Kontoyiannis, Dimitrios P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Clinical Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355575/
https://ncbi.nlm.nih.gov/pubmed/30455245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01896-18
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