Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon

Mefloquine was evaluated as an alternative for intermittent preventive treatment of malaria in pregnancy (IPTp) due to increasing resistance against the first-line drug sulfadoxine-pyrimethamine (SP). This study determined the pharmacokinetic characteristics of the mefloquine stereoisomers and the m...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ramharter, Michael, Schwab, Matthias, Mombo-Ngoma, Ghyslain, Zoleko Manego, Rella, Akerey-Diop, Daisy, Basra, Arti, Mackanga, Jean-Rodolphe, Würbel, Heike, Wojtyniak, Jan-Georg, Gonzalez, Raquel, Hofmann, Ute, Geditz, Mirjam, Matsiegui, Pierre-Blaise, Kremsner, Peter G., Menendez, Clara, Kerb, Reinhold, Lehr, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355560/
https://ncbi.nlm.nih.gov/pubmed/30455233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01113-18
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