Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon

Mefloquine was evaluated as an alternative for intermittent preventive treatment of malaria in pregnancy (IPTp) due to increasing resistance against the first-line drug sulfadoxine-pyrimethamine (SP). This study determined the pharmacokinetic characteristics of the mefloquine stereoisomers and the m...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Ramharter, Michael, Schwab, Matthias, Mombo-Ngoma, Ghyslain, Zoleko Manego, Rella, Akerey-Diop, Daisy, Basra, Arti, Mackanga, Jean-Rodolphe, Würbel, Heike, Wojtyniak, Jan-Georg, Gonzalez, Raquel, Hofmann, Ute, Geditz, Mirjam, Matsiegui, Pierre-Blaise, Kremsner, Peter G., Menendez, Clara, Kerb, Reinhold, Lehr, Thorsten
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355560/
https://ncbi.nlm.nih.gov/pubmed/30455233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01113-18
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