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Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo

Hematopoietic stem cells constitute a unique subpopulation of blood cells that can give rise to all types of mature cells in response to physiological demands. However, the intrinsic molecular machinery that regulates this transformative property remains elusive. In this paper, we demonstrate that s...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Wang, Xiaomin, Gao, Yanan, Gao, Juan, Li, Minghao, Zhou, Mi, Wang, Jinhong, Pang, Yakun, Cheng, Hui, Yuan, Chase, Chu, Yajing, Jiang, Yu, Zhou, Jianfeng, Luo, Hongbo R., Ju, Zhenyu, Cheng, Tao, Yuan, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355497/
https://ncbi.nlm.nih.gov/pubmed/30262562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.194811
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