Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B

Abnormal alternative splicing (AS) caused by alterations to splicing factors contributes to tumor progression. Serine/arginine splicing factor 1 (SRSF1) has emerged as a key oncodriver in numerous solid tumors, leaving its roles and mechanisms largely obscure in glioma. Here, we demonstrate that SRS...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Zhou, Xuexia, Wang, Run, Li, Xuebing, Yu, Lin, Hua, Dan, Sun, Cuiyun, Shi, Cuijuan, Luo, Wenjun, Rao, Chun, Jiang, Zhendong, Feng, Ying, Wang, Qian, Yu, Shizhu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355305/
https://ncbi.nlm.nih.gov/pubmed/30481162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120279
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