Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation

Persistent, unresolved inflammation in adipose tissue is a major contributor to obesity-associated metabolic complications. However, the molecular links between lipid-overloaded adipocytes and inflammatory immune cells in obese adipose tissues remain elusive. Here we identified adipocyte-secreted mi...

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Udgivet i:J Clin Invest
Main Authors: Pan, Yong, Hui, Xiaoyan, Hoo, Ruby Lai Chong, Ye, Dewei, Chan, Cyrus Yuk Cheung, Feng, Tianshi, Wang, Yu, Lam, Karen Siu Ling, Xu, Aimin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355214/
https://ncbi.nlm.nih.gov/pubmed/30667374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123069
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