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OR01-3 MicroRNA-34a-Mediated FGF21 Resistance in the Adipose Tissue Contributes to Insulin Resistance and Hypoadiponectinemia in Diet-Induced Obesity
Background and Objective: Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on glucose and lipid homeostasis, in part mediated through its stimulatory effect on adiponectin secretion. However, FGF21 circulating levels are paradoxically elevated in obesity, t...
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| Опубликовано в: : | J Endocr Soc |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Endocrine Society
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6555059/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR01-3 |
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