Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

Papillon-Lefèvre syndrome (PLS) is characterized by nonfunctional neutrophil serine proteases (NSPs) and fulminant periodontal inflammation of unknown cause. Here we investigated neutrophil extracellular trap (NET)-associated aggregation and cytokine/chemokine-release/degradation by normal and NSP-d...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Hahn, Jonas, Schauer, Christine, Czegley, Christine, Kling, Lasse, Petru, Lenka, Schmid, Benjamin, Weidner, Daniela, Reinwald, Christiane, Biermann, Mona H. C., Blunder, Stefan, Ernst, Jürgen, Lesner, Adam, Bäuerle, Tobias, Palmisano, Ralf, Christiansen, Silke, Herrmann, Martin, Bozec, Aline, Gruber, Robert, Schett, Georg, Hoffmann, Markus H.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355082/
https://ncbi.nlm.nih.gov/pubmed/30130433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800752R
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