Blood-borne phagocytes internalize urate microaggregates and prevent intravascular NETosis by urate crystals

Hyperuricemia is strongly linked to cardiovascular complications including atherosclerosis and thrombosis. In individuals with hyperuricemia, needle-shaped monosodium urate crystals (nsMSU) frequently form within joints or urine, giving rise to gouty arthritis or renal calculi, respectively. These n...

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Publicat a:Sci Rep
Autors principals: Pieterse, Elmar, Jeremic, Ivica, Czegley, Christine, Weidner, Daniela, Biermann, Mona H.C., Veissi, Susan, Maueröder, Christian, Schauer, Christine, Bilyy, Rostyslav, Dumych, Tetiana, Hoffmann, Markus, Munoz, Luis E., Bengtsson, Anders A., Schett, Georg, van der Vlag, Johan, Herrmann, Martin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137018/
https://ncbi.nlm.nih.gov/pubmed/27917897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38229
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