Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target

Hepatitis E virus (HEV) infection has emerged as a global health problem. However, no approved medication is available, and the infection biology remains largely elusive. Electron transport chain (ETC), a key component of the mitochondria, is the main site that produces ATP and reactive oxygen speci...

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Veröffentlicht in:FASEB J
Hauptverfasser: Qu, Changbo, Zhang, Shaoshi, Wang, Wenshi, Li, Meng, Wang, Yijin, van der Heijde-Mulder, Marieke, Shokrollahi, Ehsan, Hakim, Mohamad S., Raat, Nicolaas J. H., Peppelenbosch, Maikel P., Pan, Qiuwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355081/
https://ncbi.nlm.nih.gov/pubmed/30070932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800620R
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