SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects

BACKGROUND: Gene-microbiome interactions are important in aetiology and pathogenesis of inflammatory bowel disease, a chronic inflammatory disorder of the gastrointestinal tract consisting of Crohn’s disease and ulcerative colitis. Scarce studies on gene-microbiome interactions show very little over...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Collij, Valerie, Imhann, Floris, Vich Vila, Arnau, Fu, Jingyuan, Dijkstra, Gerard, Festen, Eleonora A. M., Voskuil, Michiel D., Daly, Mark J., Xavier, Ramnik J., Wijmenga, Cisca, Zhernakova, Alexandra, Weersma, Rinse K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354981/
https://ncbi.nlm.nih.gov/pubmed/30703110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211328
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