Analyzing the Clinical Actionability of Germline Pharmacogenomic Findings in Oncology

BACKGROUND: Germline and tumor pharmacogenomics impact drug responses, but germline markers less commonly guide oncology prescribing. We hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing clinical implementation opportunities. METHO...

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Publicado en:Cancer
Autores principales: Wellmann, Rebecca, Borden, Brittany A., Danahey, Keith, Nanda, Rita, Polite, Blase, Stadler, Walter M., Ratain, Mark J., O’Donnell, Peter H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354920/
https://ncbi.nlm.nih.gov/pubmed/29742281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31382
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