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Analyzing the Clinical Actionability of Germline Pharmacogenomic Findings in Oncology

BACKGROUND: Germline and tumor pharmacogenomics impact drug responses, but germline markers less commonly guide oncology prescribing. We hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing clinical implementation opportunities. METHO...

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Bibliografski detalji
Izdano u:Cancer
Glavni autori: Wellmann, Rebecca, Borden, Brittany A., Danahey, Keith, Nanda, Rita, Polite, Blase, Stadler, Walter M., Ratain, Mark J., O’Donnell, Peter H.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354920/
https://ncbi.nlm.nih.gov/pubmed/29742281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31382
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