Imidazopyridines as Potent KDM5 Demethylase Inhibitors Promoting Reprogramming Efficiency of Human iPSCs

Pioneering human induced pluripotent stem cell (iPSC)-based pre-clinical studies have raised safety concerns and pinpointed the need for safer and more efficient approaches to generate and maintain patient-specific iPSCs. One approach is searching for compounds that influence pluripotent stem cell r...

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Pubblicato in:iScience
Autori principali: Dabiri, Yasamin, Gama-Brambila, Rodrigo A., Taškova, Katerina, Herold, Kristina, Reuter, Stefanie, Adjaye, James, Utikal, Jochen, Mrowka, Ralf, Wang, Jichang, Andrade-Navarro, Miguel A., Cheng, Xinlai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354736/
https://ncbi.nlm.nih.gov/pubmed/30685712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.01.012
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