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HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarction
BACKGROUND: Epigenetic histone acetylation is a major event controlling cell functions, such as metabolism, differentiation and repair. Here, we aim to determine whether Valproic acid (VPA), a FDA approved inhibitor of histone deacetylation for bipolar disease, could protect heart against myocardial...
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| Veröffentlicht in: | EBioMedicine |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6354709/ https://ncbi.nlm.nih.gov/pubmed/30552062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.12.003 |
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