The partial inhibition of hypothalamic IRX3 exacerbates obesity

BACKGROUND: The Iroquois homeobox 3 (Irx3) gene has been identified as a functional long-range target of obesity-associated variants within the fat mass and obesity-associated protein (FTO) gene. It is highly expressed in the hypothalamus, and both whole-body knockout and hypothalamic restricted abr...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: de Araujo, Thiago Matos, Razolli, Daniela S., Correa-da-Silva, Felipe, de Lima-Junior, Jose C., Gaspar, Rodrigo S., Sidarta-Oliveira, Davi, Victorio, Sheila C., Donato, Jose, Kim, Young-Bum, Velloso, Licio A.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354701/
https://ncbi.nlm.nih.gov/pubmed/30522931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.048
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