A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease

BACKGROUND: It is widely accepted that cognitive and memory deficits in Alzheimer's disease (AD) primarily result from synaptic failure. However, the mechanisms that underlie synaptic and cognitive dysfunction remain unclear. METHODS: We utilized molecular biology techniques, electrophysiologic...

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Vydáno v:EBioMedicine
Hlavní autoři: Song, Yunping, Hu, Mei, Zhang, Jian, Teng, Zhao-qian, Chen, Chu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354659/
https://ncbi.nlm.nih.gov/pubmed/30522932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.059
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