ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans

Drebrin (DBN) regulates cytoskeletal functions during neuronal development, and is thought to contribute to structural and functional synaptic changes associated with aging and Alzheimer’s disease. Here we show that DBN coordinates stress signalling with cytoskeletal dynamics, via a mechanism involv...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kreis, Patricia, Gallrein, Christian, Rojas-Puente, Eugenia, Mack, Till G. A., Kroon, Cristina, Dinkel, Viktor, Willmes, Claudia, Murk, Kai, tom-Dieck, Susanne, Schuman, Erin M., Kirstein, Janine, Eickholt, Britta J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353951/
https://ncbi.nlm.nih.gov/pubmed/30700723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08420-w
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