ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans

Drebrin (DBN) regulates cytoskeletal functions during neuronal development, and is thought to contribute to structural and functional synaptic changes associated with aging and Alzheimer’s disease. Here we show that DBN coordinates stress signalling with cytoskeletal dynamics, via a mechanism involv...

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Publicat a:Nat Commun
Autors principals: Kreis, Patricia, Gallrein, Christian, Rojas-Puente, Eugenia, Mack, Till G. A., Kroon, Cristina, Dinkel, Viktor, Willmes, Claudia, Murk, Kai, tom-Dieck, Susanne, Schuman, Erin M., Kirstein, Janine, Eickholt, Britta J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353951/
https://ncbi.nlm.nih.gov/pubmed/30700723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08420-w
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