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The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography

Determining the path of single ribonucleoprotein (RNP) particles through the 100 nm-wide nuclear pore complex (NPC) by fluorescence microscopy remains challenging due to resolution limitation and RNP labeling constraints. By using high-pressure freezing and electron tomography, here we captured snap...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Delavoie, Franck, Soldan, Vanessa, Rinaldi, Dana, Dauxois, Jean-Yves, Gleizes, Pierre-Emmanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353910/
https://ncbi.nlm.nih.gov/pubmed/30700705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08342-7
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