Phase 1 trial of olaparib and oral cyclophosphamide in BRCA breast cancer, recurrent BRCA ovarian cancer, non-BRCA triple-negative breast cancer, and non-BRCA ovarian cancer

BACKGROUND: We conducted a Phase 1 study to evaluate safety and activity of olaparib tablets and oral cyclophosphamide. METHODS: Patients had metastatic breast cancer (BC) or recurrent high-grade serous ovarian cancer (HGSOC), performance status 0–2, and ≤3 lines of prior therapy. Patients were trea...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Br J Cancer
Κύριοι συγγραφείς: Lee, Chee Khoon, Scott, Clare, Lindeman, Geoffrey J., Hamilton, Anne, Lieschke, Elizabeth, Gibbs, Emma, Asher, Rebecca, Badger, Heath, Paterson, Robin, Macnab, Lauren, Kwan, Edmond Michael, Francis, Prudence A., Boyle, Frances, Friedlander, Michael
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2019
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353881/
https://ncbi.nlm.nih.gov/pubmed/30655615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0349-6
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια