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Circulating tumour cells and their association with bone metastases in patients with neuroendocrine tumours

BACKGROUND: Bone metastases are associated with a worse outcome in patients with neuroendocrine tumours (NETs). Tumour overexpression of C-X-C chemokine receptor 4 (CXCR4) appears predictive of skeletal involvement. We investigated the role of circulating tumour cells (CTCs) and CXCR4 expression on...

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Détails bibliographiques
Publié dans:Br J Cancer
Auteurs principaux: Rizzo, Francesca M., Vesely, Clare, Childs, Alexa, Marafioti, Teresa, Khan, Mohid S., Mandair, Dalvinder, Cives, Mauro, Ensell, Leah, Lowe, Helen, Akarca, Ayse U., Luong, TuVinh, Caplin, Martyn, Toumpanakis, Christos, Krell, Daniel, Thirlwell, Christina, Silvestris, Franco, Hartley, John A., Meyer, Tim
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353867/
https://ncbi.nlm.nih.gov/pubmed/30636773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0367-4
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