Circulating tumour cells and their association with bone metastases in patients with neuroendocrine tumours

BACKGROUND: Bone metastases are associated with a worse outcome in patients with neuroendocrine tumours (NETs). Tumour overexpression of C-X-C chemokine receptor 4 (CXCR4) appears predictive of skeletal involvement. We investigated the role of circulating tumour cells (CTCs) and CXCR4 expression on...

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Publicado en:Br J Cancer
Autores principales: Rizzo, Francesca M., Vesely, Clare, Childs, Alexa, Marafioti, Teresa, Khan, Mohid S., Mandair, Dalvinder, Cives, Mauro, Ensell, Leah, Lowe, Helen, Akarca, Ayse U., Luong, TuVinh, Caplin, Martyn, Toumpanakis, Christos, Krell, Daniel, Thirlwell, Christina, Silvestris, Franco, Hartley, John A., Meyer, Tim
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353867/
https://ncbi.nlm.nih.gov/pubmed/30636773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0367-4
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