Using Stepwise Pharmacogenomics and Proteomics to Predict Hepatitis C Treatment Response in Difficult to Treat Patient Populations

PURPOSE: In the interferon era of hepatitis C virus (HCV) therapies, genotype/subtype, cirrhosis, prior treatment failure, sex, and race predicted relapse. Our objective is to validate a targeted proteomics platform of 17 peptides to predict sustained virologic response (SVR). EXPERIMENTAL DESIGN: S...

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Vydáno v:Proteomics Clin Appl
Hlavní autoři: Naggie, Susanna, Clement, Meredith, Lusk, Sam, Osinusi, Anu, Himmel, Tiffany, Lucas, Joseph E., Thompson, Will J., Dubois, Laura, Moseley, M. Arthur, Clark, Paul J., Kottilil, Shyam, Patel, Keyur
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353701/
https://ncbi.nlm.nih.gov/pubmed/30058111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201800006
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