Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors

Fatty Acid Amide Hydrolase (FAAH) is a serine hydrolase that plays a key role in controlling endogenous levels of endocannabinoids. FAAH inhibition is considered a powerful approach to enhance the endocannabinoid signalling, and therefore it has been largely studied as a potential target for the tre...

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Bibliographische Detailangaben
Veröffentlicht in:J Enzyme Inhib Med Chem
Hauptverfasser: Deplano, Alessandro, Cipriano, Mariateresa, Moraca, Federica, Novellino, Ettore, Catalanotti, Bruno, Fowler, Christopher J., Onnis, Valentina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352954/
https://ncbi.nlm.nih.gov/pubmed/30688118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1532418
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