Inhibition of protein phosphatase-1 and -2A by ellagitannins: structure-inhibitory potency relationships and influences on cellular systems

Several ellagitannins inhibited the activity of protein phosphatase-1 (PP1) and -2 A (PP2A) catalytic subunits (PP1c and PP2Ac) with preferential suppression of PP1c over PP2Ac. The inhibitory potency for PP1c followed the order of tellimagrandin I > mahtabin A > praecoxin B > 1.2-Di-O-gall...

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Foilsithe in:J Enzyme Inhib Med Chem
Main Authors: Kónya, Zoltán, Bécsi, Bálint, Kiss, Andrea, Horváth, Dániel, Raics, Mária, Kövér, Katalin E., Lontay, Beáta, Erdődi, Ferenc
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2019
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352937/
https://ncbi.nlm.nih.gov/pubmed/30696301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1557653
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