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Human Antibody-Based Chemically Induced Dimerizers for Cell Therapeutic Applications

Chemically induced dimerizers (CIDs) have emerged as one of the most powerful tools to artificially regulate signaling pathways in cells; however, currently available CID systems lack the properties desired for use in regulating cellular therapies. Here, we report the development of human antibody-b...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Hill, Zachary B, Martinko, Alexander J, Nguyen, Duy P, Wells, James A
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352901/
https://ncbi.nlm.nih.gov/pubmed/29200207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2529
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