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Inhibition of pSTAT1 by tofacitinib accounts for the early improvement of experimental chronic synovitis
BACKGROUND: In order to gain insight into the early effects drawn by JAK inhibitors on intra-joint JAK/STAT-dependent signaling, we sought synovial activation of STATs and their end-products, along with their modification with tofacitinib (TOFA), at flare-up in antigen induced arthritis (AIA). New Z...
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| Udgivet i: | J Inflamm (Lond) |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6352431/ https://ncbi.nlm.nih.gov/pubmed/30728752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12950-019-0206-2 |
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