Tofacitinib restores the inhibition of reverse cholesterol transport induced by inflammation: understanding the lipid paradox associated with rheumatoid arthritis

BACKGROUND AND PURPOSE: Patients with active rheumatoid arthritis (RA) have increased cardiovascular mortality, paradoxically associated with reduced circulating lipid levels. The JAK inhibitor tofacitinib ameliorates systemic and joint inflammation in RA with a concomitant increase in serum lipids....

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Pérez‐Baos, S, Barrasa, J I, Gratal, P, Larrañaga‐Vera, A, Prieto‐Potin, I, Herrero‐Beaumont, G, Largo, R
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573422/
https://ncbi.nlm.nih.gov/pubmed/28646516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13932
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