Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin

OBJECTIVE: Campylobacter jejuni produces a genotoxin, cytolethal distending toxin (CDT), which has DNAse activity and causes DNA double-strand breaks. Although C. jejuni infection has been shown to promote intestinal inflammation, the impact of this bacterium on carcinogenesis has never been examine...

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發表在:Gut
Main Authors: He, Zhen, Gharaibeh, Raad Z, Newsome, Rachel C, Pope, Jllian L, Dougherty, Michael W, Tomkovich, Sarah, Pons, Benoit, Mirey, Gladys, Vignard, Julien, Hendrixson, David R, Jobin, Christian
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2019
主題:
Colon
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352414/
https://ncbi.nlm.nih.gov/pubmed/30377189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2018-317200
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