Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs

Despite the significant achievements in chemotherapy, cancer remains one of the leading causes of death. Target therapy revolutionized this field, but efficiencies of target drugs show dramatic variation among individual patients. Personalization of target therapies remains, therefore, a challenge i...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Zolotovskaia, Marianna A., Sorokin, Maxim I., Emelianova, Anna A., Borisov, Nikolay M., Kuzmin, Denis V., Borger, Pieter, Garazha, Andrew V., Buzdin, Anton A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351482/
https://ncbi.nlm.nih.gov/pubmed/30728774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00001
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