Rosiglitazone reverses high fat diet-induced changes in BMAL1 function in muscle, fat, and liver tissue in mice

OBJECTIVE: Nutrient challenge in the form of a high fat (HF) diet causes a reversible reprogramming of the hepatic circadian clock. This depends in part on changes in the recruitment of the circadian transcription factor BMAL1 to genome targets, though the causes and extent of disruption to hepatic...

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Veröffentlicht in:Int J Obes (Lond)
Hauptverfasser: Ribas-Latre, Aleix, Fekry, Baharan, Kwok, Christopher, Baumgartner, Corrine, Shivshankar, Samay, Sun, Kai, Chen, Zheng, Eckel-Mahan, Kristin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351224/
https://ncbi.nlm.nih.gov/pubmed/29795456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-018-0090-5
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