Serum Angiopoietin-2 Predicts Mortality and Kidney Outcomes in Decompensated Cirrhosis

BACKGROUND/AIMS: Acute kidney injury in decompensated cirrhosis has limited therapeutic options and novel mechanistic targets are urgently needed. Angiopoietin-2 is a context-specific antagonist of Tie2, a receptor that signals vascular quiescence. Considering the prominence of vascular destabilizat...

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Publicado no:Hepatology
Main Authors: Allegretti, Andrew S., Parada, Xavier Vela, Ortiz, Guillermo A., Long, Joshua, Krinsky, Scott, Zhao, Sophia, Fuchs, Bryan C., Sojoodi, Mozhdeh, Zhang, Dongsheng, Karumanchi, S. Ananth, Kalim, Sahir, Nigwekar, Sagar U., Thadhani, Ravi I., Parikh, Samir M., Chung, Raymond T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351209/
https://ncbi.nlm.nih.gov/pubmed/30141205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30230
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