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Screening-based approach to discover effective platinum-based chemotherapies for cancers with poor prognosis

Drug combinations are extensively used to treat cancer and are often selected according to complementary mechanisms. Here, we describe a cell-based high-throughput screening assay for identification of synergistic combinations between broadly applied platinum-based chemotherapeutics and drugs from a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Varbanov, Hristo P., Kuttler, Fabien, Banfi, Damiano, Turcatti, Gerardo, Dyson, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350982/
https://ncbi.nlm.nih.gov/pubmed/30695050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211268
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