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The Role of Syk in Peripheral T Cells

The aim of this study was to understand how Syk affects peripheral T cell function. T cells from Syk (−/−) chimeric mice and DR1 Syk(fl/fl) CD4(cre) conditional mice gave strong CD3-induced Th1, Th2, and Th17 cytokine responses. However, an altered peptide ligand (APL) of human CII (256 276) with tw...

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Detalles Bibliográficos
Publicado en:Clin Immunol
Main Authors: Park, Jeoung-Eun, Majumdar, Sirshendu, Brand, David D., Rosloniec, Edward F., Yi, Ae-Kyung, Stuart, John M., Kang, Andrew H., Myers, Linda K.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350940/
https://ncbi.nlm.nih.gov/pubmed/29673901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2018.04.007
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