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Synthesis and biological activity of methylated derivatives of the Pseudomonas metabolites HHQ, HQNO and PQS

Selectively methylated analogues of naturally occurring 2-heptyl-4(1H)-quinolones, which are alkaloids common within the Rutaceae family and moreover are associated with quorum sensing and virulence of the human pathogen Pseudomonas aeruginosa, have been prepared. While the synthesis by direct methy...

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Bibliografiske detaljer
Udgivet i:Beilstein J Org Chem
Main Authors: Thierbach, Sven, Wienhold, Max, Fetzner, Susanne, Hennecke, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350858/
https://ncbi.nlm.nih.gov/pubmed/30745993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.18
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