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Synthesis and biological activity of methylated derivatives of the Pseudomonas metabolites HHQ, HQNO and PQS

Selectively methylated analogues of naturally occurring 2-heptyl-4(1H)-quinolones, which are alkaloids common within the Rutaceae family and moreover are associated with quorum sensing and virulence of the human pathogen Pseudomonas aeruginosa, have been prepared. While the synthesis by direct methy...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Thierbach, Sven, Wienhold, Max, Fetzner, Susanne, Hennecke, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350858/
https://ncbi.nlm.nih.gov/pubmed/30745993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.18
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