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Quantifying Shear-Induced Deformation and Detachment of Individual Adherent Sickle Red Blood Cells

Vaso-occlusive crisis, a common painful complication of sickle cell disease, is a complex process triggered by intercellular adhesive interactions among blood cells and the endothelium in all human organs (e.g., the oxygen-rich lung as well as hypoxic systems such as liver and kidneys). We present a...

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Veröffentlicht in:Biophys J
Hauptverfasser: Deng, Yixiang, Papageorgiou, Dimitrios P., Chang, Hung-Yu, Abidi, Sabia Z., Li, Xuejin, Dao, Ming, Karniadakis, George Em
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350013/
https://ncbi.nlm.nih.gov/pubmed/30612714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.12.008
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