Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation

The three-dimensional organization of the genome contributes to its maintenance and regulation. While chromosomal regions associate with nucleolar ribosomal RNA genes (rDNA), the biological significance of rDNA-genome interactions and whether they are dynamically regulated during disease remain uncl...

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Publicado en:Commun Biol
Autores principales: Diesch, Jeannine, Bywater, Megan J., Sanij, Elaine, Cameron, Donald P., Schierding, William, Brajanovski, Natalie, Son, Jinbae, Sornkom, Jirawas, Hein, Nadine, Evers, Maurits, Pearson, Richard B., McArthur, Grant A., Ganley, Austen R. D., O’Sullivan, Justin M., Hannan, Ross D., Poortinga, Gretchen
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349880/
https://ncbi.nlm.nih.gov/pubmed/30701204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0284-y
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