TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice

Transient Receptor Potential Canonical 5 (TRPC5) is a subunit of a Ca(2+)-permeable non-selective cationic channel which negatively regulates adiponectin but not leptin in mice fed chow diet. Adiponectin is a major anti-inflammatory mediator and so we hypothesized an effect of TRPC5 on the inflammat...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Rode, Baptiste, Yuldasheva, Nadira Y., Baxter, Paul D., Sedo, Alicia, Ainscough, Justin F., Shires, Michael, Kearney, Mark T., Bailey, Marc A., Wheatcroft, Stephen B., Beech, David J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349875/
https://ncbi.nlm.nih.gov/pubmed/30692584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37299-8
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