TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice

Transient Receptor Potential Canonical 5 (TRPC5) is a subunit of a Ca(2+)-permeable non-selective cationic channel which negatively regulates adiponectin but not leptin in mice fed chow diet. Adiponectin is a major anti-inflammatory mediator and so we hypothesized an effect of TRPC5 on the inflammat...

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Vydáno v:Sci Rep
Hlavní autoři: Rode, Baptiste, Yuldasheva, Nadira Y., Baxter, Paul D., Sedo, Alicia, Ainscough, Justin F., Shires, Michael, Kearney, Mark T., Bailey, Marc A., Wheatcroft, Stephen B., Beech, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349875/
https://ncbi.nlm.nih.gov/pubmed/30692584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37299-8
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