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Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells

Bone marrow-derived allogeneic (donor derived) mesenchymal stem cells (MSCs) are immunoprivileged and are considered to be prominent candidates for regenerative therapy for numerous degenerative diseases. Even though the outcome of initial allogeneic MSCs based clinical trials was encouraging, the o...

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Bibliografiska uppgifter
I publikationen:Cell Death Dis
Huvudupphovsmän: Abu-El-Rub, Ejlal, Sequiera, Glen Lester, Sareen, Niketa, Yan, Weiang, Moudgil, Meenal, Sabbir, Mohammad Golam, Dhingra, Sanjiv
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349874/
https://ncbi.nlm.nih.gov/pubmed/30692516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1359-x
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