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Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells

Bone marrow-derived allogeneic (donor derived) mesenchymal stem cells (MSCs) are immunoprivileged and are considered to be prominent candidates for regenerative therapy for numerous degenerative diseases. Even though the outcome of initial allogeneic MSCs based clinical trials was encouraging, the o...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Abu-El-Rub, Ejlal, Sequiera, Glen Lester, Sareen, Niketa, Yan, Weiang, Moudgil, Meenal, Sabbir, Mohammad Golam, Dhingra, Sanjiv
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349874/
https://ncbi.nlm.nih.gov/pubmed/30692516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1359-x
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