Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells

Bone marrow-derived allogeneic (donor derived) mesenchymal stem cells (MSCs) are immunoprivileged and are considered to be prominent candidates for regenerative therapy for numerous degenerative diseases. Even though the outcome of initial allogeneic MSCs based clinical trials was encouraging, the o...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Abu-El-Rub, Ejlal, Sequiera, Glen Lester, Sareen, Niketa, Yan, Weiang, Moudgil, Meenal, Sabbir, Mohammad Golam, Dhingra, Sanjiv
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349874/
https://ncbi.nlm.nih.gov/pubmed/30692516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1359-x
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