Cancer cell-derived immunoglobulin G activates platelets by binding to platelet FcγRIIa

Tumor-associated thrombosis is the second leading risk factor for cancer patient death, and platelets activity is abnormal in cancer patients. Discovering the mechanism of platelet activation and providing effective targets for therapy are urgently needed. Cancer cell- derived IgG has been reported...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Miao, Shuo, Shu, Dan, Zhu, Ying, Lu, Meng, Zhang, Qingsong, Pei, Youliang, He, Ao-Di, Ma, Rong, Zhang, Bixiang, Ming, Zhang-Yin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349849/
https://ncbi.nlm.nih.gov/pubmed/30692520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1367-x
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