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Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation

Acute respiratory distress syndrome (ARDS) is characterized by an excessive acute inflammatory response in lung parenchyma, which ultimately leads to refractory hypoxemia. One of the earliest abnormalities seen in lung injury is the elevated levels of inflammatory cytokines, among them, the soluble...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Pooladanda, Venkatesh, Thatikonda, Sowjanya, Bale, Swarna, Pattnaik, Bijay, Sigalapalli, Dilep Kumar, Bathini, Nagendra Babu, Singh, Shashi Bala, Godugu, Chandraiah
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349848/
https://ncbi.nlm.nih.gov/pubmed/30692512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1247-9
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