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Tyrosine hydroxylase inhibition in substantia nigra decreases movement frequency

Reduced movement frequency or physical activity (bradykinesia) occurs with high prevalence in the elderly. However, loss of striatal tyrosine hydroxylase (TH) in aging humans, non-human primates, or rodents does not reach the ~80% loss threshold associated with bradykinesia onset in Parkinson’s dise...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Neurobiol
Päätekijät: Salvatore, Michael F, McInnis, Tamara R., Cantu, Mark A., Apple, Deana M., Pruett, Brandon S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349536/
https://ncbi.nlm.nih.gov/pubmed/30056575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1256-9
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