Dopamine Pathology in Schizophrenia: Analysis of Total and Phosphorylated Tyrosine Hydroxylase in the Substantia Nigra

Introduction: Despite the importance of dopamine neurotransmission in schizophrenia, very few studies have addressed anomalies in the mesencephalic dopaminergic neurons of the substantia nigra/ventral tegmental area (SN/VTA). Tyrosine hydroxylase (TH) is the rate-limiting enzyme for the production o...

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Autors principals: Perez-Costas, Emma, Melendez-Ferro, Miguel, Rice, Matthew W., Conley, Robert R., Roberts, Rosalinda C.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Psychiatry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321522/
https://ncbi.nlm.nih.gov/pubmed/22509170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2012.00031
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