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Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation

Focal inflammation and remyelination failure are major hallmarks of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). In this study, we found that leonurine, a bioactive alkaloid, alleviated EAE disease severity along with reduced central nervous system inflam...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Jin, Min, Li, Qian, Gu, Yuting, Wan, Bing, Huang, Jiefang, Xu, Xuanbai, Huang, Rui, Zhang, Yanyun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6349161/
https://ncbi.nlm.nih.gov/pubmed/30556290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14053
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