18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination

Microglia are intrinsic immune cells in the central nervous system (CNS). The under controlled microglia activation plays important roles in inflammatory demyelination diseases, such as multiple sclerosis (MS). However, the means to modulate microglia activation as a therapeutic modality and the und...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Jieru, Cai, Wei, Jin, Min, Xu, Jingwei, Wang, Yanan, Xiao, Yichuan, Hao, Li, Wang, Bei, Zhang, Yanyun, Han, Jie, Huang, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557075/
https://ncbi.nlm.nih.gov/pubmed/26329786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13713
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